Proposal Requirement 2 Example: Antibiotic Alternative

Writer: Jana Chan

Instagram: @jana.chan_



Antibiotics, with its ability to slow the growth of bacterial infections in the human body, have long been used to save countless lives. However, increasing overuse and misuse of these essential antimicrobials are leading to an increase in antibiotic-resistant bacteria that threatens the lives of many as well as the future of the healthcare industry. Therefore, an alternative to antibiotics must be found. Many solutions have been designed to help solve this issue, such as bacteriophage therapy and the use of predatory bacteria, but predatory bacteria seems to be the most promising. The goal of this study will be to find a safe and effective way to utilize the techniques already established through CRISPR-Cas9 technology and previous bacterial genome editing research to create the ideal predatory bacteria as a potential substitute for antibiotics. Bdellovibrio bacteriovorus, an abundant predator bacterial species, will be the main candidate, as it already contains many advantageous traits (Harini et al., 2013).


The purpose of an abstract is to condense one’s proposal into a short summary (Envision has a 150-word maximum) so the reader can quickly understand key points about the proposal and determine relevance. Thus, an abstract should highlight a proposal’s most important components. The author of this example achieves this by first providing a brief context to the issue, such as explaining its necessity, its potential impact if nothing was done, and some past solutions. She also clearly states the goal of the proposal and how she plans to achieve it. It is important to write concisely and with as much thought as possible to cover all areas of importance since the word count requirement will limit space. In this example, she focuses too much on context and could have done better by summarizing her context (such as removing unnecessary adjectives or combining similar sentences into one sentence) more concisely to instead concentrate on the methodology/procedure itself.


Aminov R. I. (2010). A brief history of the antibiotic era: lessons learned and challenges for the future.

Frontiers in microbiology, 1, 134.

Allen, H. K. (2017). Alternatives to antibiotics: Why and how. NAM Perspectives. Discussion Paper,

National Academy of Medicine, Washington, DC.

Harini, K., Ajila, V., & Hegde, S. (2013). Bdellovibrio bacteriovorus: A future antimicrobial

agent?. Journal of Indian Society of Periodontology, 17(6), 823–825.

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